Pronunciation: a-SEET-a-MIN-oh-fen/pen-TAZ-oh-seen
Generic Name: Acetaminophen/Pentazocine
Brand Name: Generic only. No brands available.
Acetaminophen/Pentazocine contains acetaminophen. Severe and sometimes fatal liver problems, including the need for liver transplant, have been reported with the use of acetaminophen. Most cases of these liver problems occurred in patients taking excessive doses of acetaminophen (more than 4,000 mg per day). Also, patients who developed these liver problems were often using more than 1 medicine that contained acetaminophen. Discuss any questions or concerns with your doctor.
Acetaminophen/Pentazocine is used for:
Relieving mild to moderate pain.
Acetaminophen/Pentazocine is a narcotic and analgesic combination. It works in the brain to reduce pain.
Do NOT use Acetaminophen/Pentazocine if:
- you are allergic to any ingredient in Acetaminophen/Pentazocine
- you have a dependence on opiates (eg, morphine) or you are taking sodium oxybate (GHB)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Acetaminophen/Pentazocine:
Some medical conditions may interact with Acetaminophen/Pentazocine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have poor health, low blood oxygen levels, high blood carbon dioxide levels, stomach pain, or severe or persistent diarrhea caused by antibiotic use (pseudomembranous colitis)
- if you have a history of a recent head injury, growths in the brain (eg, tumors), increased pressure in the brain, or seizures
- if you have a history of stomach or bowel problems (eg, inflammation, stomach or bowel surgery), lung or breathing problems (eg, asthma, chronic obstructive pulmonary disease [COPD]), liver problems (eg, hepatitis), kidney problems, heart problems (eg, cor pulmonale), a recent heart attack, high blood pressure, the blood disease porphyria, thyroid problems, adrenal gland problems (eg, Addison disease), an enlarged prostate or benign prostatic hypertrophy (BPH), gallbladder problems, inflammation of the pancreas (pancreatitis), urinary blockage or trouble urinating, or curvature of the spine (scoliosis)
- if you have a history of mental or mood problems, suicidal thoughts or actions, or drug or alcohol abuse or dependence
- if you are in alcohol withdrawal or if you smoke
- if you have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the past 14 days
Some MEDICINES MAY INTERACT with Acetaminophen/Pentazocine. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Anticholinergic medicines (eg, oxybutynin, scopolamine) because the risk of severe constipation or trouble urinating may be increased
- Cimetidine, certain nausea medicines (eg, ondansetron), phenothiazines (eg, chlorpromazine), sodium oxybate (GHB), or other narcotic medicines (eg, oxycodone) because they may increase the risk of Acetaminophen/Pentazocine's side effects
- Anticoagulants (eg, warfarin), MAOIs (eg, phenelzine), or sibutramine because the risk of their side effects may be increased by Acetaminophen/Pentazocine
- Naltrexone or rifamycins (eg, rifampin) because they may decrease the effectiveness of Acetaminophen/Pentazocine
- Methadone or other narcotic medicines (eg, oxycodone) because their effectiveness may be decreased by Acetaminophen/Pentazocine
- Medicines that may harm the liver (eg, methotrexate, ketoconazole, isoniazid, certain medicines for HIV infection) because the risk of liver side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the liver
This may not be a complete list of all interactions that may occur. Ask your health care provider if Acetaminophen/Pentazocine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Acetaminophen/Pentazocine:
Use Acetaminophen/Pentazocine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Acetaminophen/Pentazocine may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- If you miss a dose of Acetaminophen/Pentazocine and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Acetaminophen/Pentazocine.
Important safety information:
- Acetaminophen/Pentazocine may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Acetaminophen/Pentazocine. Using Acetaminophen/Pentazocine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
- Avoid drinking alcohol while you are taking Acetaminophen/Pentazocine.
- Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while taking Acetaminophen/Pentazocine; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Do not change your dose or change how often you take Acetaminophen/Pentazocine without checking with your doctor.
- If you have been taking Acetaminophen/Pentazocine for a prolonged period of time, do not stop taking it without checking with your doctor.
- Tell your doctor or dentist that you take Acetaminophen/Pentazocine before you receive any medical or dental care, emergency care, or surgery.
- Acetaminophen/Pentazocine contains acetaminophen. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains acetaminophen. If it does or if you are uncertain, contact your doctor or pharmacist.
- Acetaminophen/Pentazocine may contain sulfites, which can cause allergic reactions in certain individuals (eg, asthma patients). If you have previously had allergic reactions to sulfites, contact your doctor or pharmacist to determine if the medicine you are taking contains sulfites.
- Acetaminophen/Pentazocine may increase your risk of seizures, especially if you have a history of seizures. Contact your doctor right away if you have a seizure while taking Acetaminophen/Pentazocine.
- Acetaminophen/Pentazocine may cause constipation. To prevent constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. Talk to your doctor about using fiber laxatives or stool softeners to prevent or treat constipation while you take Acetaminophen/Pentazocine.
- Use Acetaminophen/Pentazocine with caution in the ELDERLY; they may be more sensitive to its effects, especially breathing problems, confusion, and hallucinations.
- Use Acetaminophen/Pentazocine with extreme caution in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Acetaminophen/Pentazocine, discuss with your doctor the benefits and risks of using Acetaminophen/Pentazocine during pregnancy. Acetaminophen/Pentazocine is found in breast milk. If you are or will be breast-feeding while you are using Acetaminophen/Pentazocine, check with your doctor or pharmacist to discuss the risks to your baby.
When used for long periods of time or at high doses, some people develop a need to continue taking Acetaminophen/Pentazocine. This is known as DEPENDENCE or addiction.
If you suddenly stop taking Acetaminophen/Pentazocine, you may experience WITHDRAWAL symptoms, including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.
Possible side effects of Acetaminophen/Pentazocine:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; dizziness; drowsiness; headache; light-headedness; nausea; sweating; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); blistered, red, peeling, or swollen skin; confusion; disorientation; fainting; fast heartbeat; hallucinations; mental or mood changes (eg, depression, exaggerated sense of well-being); seizures; severe or persistent drowsiness, dizziness, light-headedness, or headache; severe stomach pain; slow or shallow breathing; tremor; trouble sleeping; trouble urinating; vision problems (eg, blurred vision); weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Acetaminophen/Pentazocine side effects (in more detail)
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include anxiety; burning, numbness, or tingling; confusion; excessive sweating; extreme fatigue; fainting; fast heartbeat; hallucinations; loss of consciousness; nausea; seizures; slow and shallow breathing; symptoms of liver problems (eg, dark urine, loss of appetite, right-sided stomach pain, yellowing of the eyes or skin); unusual bruising or bleeding; unusual drowsiness, dizziness, headache, or light-headedness; unusual thoughts; vomiting.
Proper storage of Acetaminophen/Pentazocine:
Store Acetaminophen/Pentazocine between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acetaminophen/Pentazocine out of the reach of children and away from pets.
General information:
- If you have any questions about Acetaminophen/Pentazocine, please talk with your doctor, pharmacist, or other health care provider.
- Acetaminophen/Pentazocine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information is a summary only. It does not contain all information about Acetaminophen/Pentazocine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
More Acetaminophen/Pentazocine resources
- Acetaminophen/Pentazocine Side Effects (in more detail)
- Acetaminophen/Pentazocine Use in Pregnancy & Breastfeeding
- Drug Images
- Acetaminophen/Pentazocine Drug Interactions
- Acetaminophen/Pentazocine Support Group
- 1 Review for Acetaminophen/Pentazocine - Add your own review/rating
Compare Acetaminophen/Pentazocine with other medications
- Pain
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