Generic Name: anidulafungin (a nid yoo luh FUN jin)
Brand Names: Eraxis
What is anidulafungin?
Anidulafungin is an antifungal antibiotic that fights infections caused by fungus.
Anidulafungin treats candida (yeast) infections in the blood, or in the stomach or esophagus.
Anidulafungin may also be used for purposes not listed in this medication guide.
What is the most important information I should know about anidulafungin?
You should not use this medication if you are allergic to anidulafungin, caspofungin (Cancidas), micafungin (Mycamine), or similar antifungal medicines.
Before using anidulafungin, tell your doctor if you have liver disease.
There may be other drugs that can interact with anidulafungin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Anidulafungin will not treat a viral infection such as the common cold or flu.
What should I discuss with my health care provider before using anidulafungin?
You should not use this medication if you are allergic to anidulafungin, caspofungin (Cancidas), micafungin (Mycamine), or similar antifungal medicines.
To make sure you can safely use anidulafungin, tell your doctor if you have liver disease.
FDA pregnancy category C. It is not known whether anidulafungin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether anidulafungin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How is anidulafungin given?
Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Anidulafungin is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
Anidulafungin is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.
Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Anidulafungin will not treat a viral infection such as the common cold or flu.
Store unmixed medicine in the refrigerator, do not freeze. After mixing anidulafungin with a diluent, store in the refrigerator and use it within 1 hour. Do not freeze.
What happens if I miss a dose?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using anidulafungin?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Anidulafungin side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using anidulafungin and call your doctor at once if you have a serious side effect such as:
bronchospasm (wheezing, chest tightness, trouble breathing);
fever, chills, body aches, flu symptoms, sores in your mouth and throat;
nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling).
Less serious side effects may include:
hot flashes;
diarrhea or constipation;
nausea, vomiting; or
pain, swelling, or irritation where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Anidulafungin Dosing Information
Usual Adult Dose for Esophageal Candidiasis:
Initial dose: 100 mg IV on Day 1
Maintenance dose: 50 mg IV once a day thereafter
Duration: Treatment should be given for a minimum of 14 days and for at least 7 days following resolution of symptoms. Treatment duration should be based on the patient's clinical response. If the patient is infected with HIV, suppressive antifungal therapy may be considered after a course of treatment to minimize the risk of relapse.
Usual Adult Dose for Candidemia:
Candidemia and other Candida infections (intraabdominal abscess and peritonitis):
Initial dose: 200 mg IV on Day 1
Maintenance dose: 100 mg IV once a day thereafter
Duration: Duration of treatment should be based on the patient's clinical response. In general, antifungal therapy should continue for at least 14 days after the last positive culture.
What other drugs will affect anidulafungin?
There may be other drugs that can interact with anidulafungin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More anidulafungin resources
- Anidulafungin Side Effects (in more detail)
- Anidulafungin Dosage
- Anidulafungin Use in Pregnancy & Breastfeeding
- Anidulafungin Drug Interactions
- Anidulafungin Support Group
- 0 Reviews for Anidulafungin - Add your own review/rating
- anidulafungin Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information
- Anidulafungin Professional Patient Advice (Wolters Kluwer)
- Anidulafungin MedFacts Consumer Leaflet (Wolters Kluwer)
- Anidulafungin Monograph (AHFS DI)
- Eraxis Prescribing Information (FDA)
- Eraxis Consumer Overview
Compare anidulafungin with other medications
- Candida Infections, Systemic
- Esophageal Candidiasis
Where can I get more information?
- Your pharmacist can provide more information about anidulafungin.
See also: anidulafungin side effects (in more detail)
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